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KMID : 0380420010250040243
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Journal of Prventive Veterinary Medicine
2001 Volume.25 No. 4 p.243 ~ p.251
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Comparison of the Phagocytic Activity and γ-Interferon Productivity in Mastitis-Resistant Cows and Mastitis-Susceptible Cows
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주이석/Joo, Yi Seok
문진산/김종택/서국현/위성환/남향미/박용호/Moon, Jin San/Kim, Jong Taek/Seo, Kook Hyun/Wee, Sung Hwan/Nam, Hyang Mi/Park, Yong Ho
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Abstract
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This study was carried out to investigate the funcion of immune cells in the cow groups of mastitis-resistant and mastitis-susceptible. The somatic cell counts were 9×10^4 SCC/ml and 4.4×10^5 SCC/ml in bovine mastitis-resistant and -susceptible cows, respectively. Phagocytic activity in both opsonized and unopsonized groups was lower in mastitis-susceptible cows than those of mastitis-resistant cows. To compare the mitogen-induced lymphoblastogenesis in blood between the matitis-resistant group and the -susceptible group, we used ConA, PHA and PWM as mitogens. There were no significant differences between the two groups. We also measured and compared the productivity of γ-interferon after stumulation of whole blood by ConA and PHA in these two groups of cows. The resistant group produced more γ-interferon than the susceptible group. This study indicated that the function of immune cells was more active in mastitis-resistant group cows compared to the mastitis-susceptible group cows.
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